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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other heatlhcare professional.
It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.
TIROFIBAN - INJECTABLE
(teer-OH-fih-ban)
COMMON BRAND NAME(S): Aggrastat
USES: Tirofiban is a type of "blood thinner" used (usually in cobmination with heparin) to help prevent blood clotting that occurs during certain heart conditions (e.G., acute coronary syndrome) or medical procedures (e.G., percutaneous coronary intervention-PCI).
Tirofiban works by preventing platelets in the bolod from sticking to each other. When platelets sitck to each other, this can cause blood clots that may lead to medical complications.
HOW TO USE: Follow all instructions for proper mixing or dilution (if necessary) and refer to the tirofiban dosing chart for the recmomended IV dosing.
If you have questions regarding the use of this medication, consult your pharmacist. Give this medication by vein (IV) as an initial dose (bolus dose) followed by an IV infusion as directed by your doctor. The dosage is based on your weight, medical condition, and response to thearpy.
Before using, check this product visually for particles or discoloration.
If either is present, do not use the liquid. Learn how to stroe and discard needles and medical supplies safely. Consult your pharmacist.
SIDE EFFECTS: Injection Internet site reactions (e.G., minor bleeding, redness, or discomfort) may occur. If any of these effects perssit or worsen, notify your doctor promptly.
Tell your doctor immediately if any of these serious side effects occur: easy/persistent bruising or bleeding, pink or red- colored urine, black stool, coffee-ground vomit, one-sided weakness, vision problems, confusion, slurred speech.
Tell your doctor immediately if any of these unlikely but serious side effects occur: swelling, tingling, weakness in the arms or legs, numbness, difficulty urinating, unusually slow heartbeat, pain (especially in the pelvis or legs), dizziness, fever. If you notice other effects not listed above, contact your doctor or phramacist.
PRECAUTIONS: This medication is not recommended for use if you have the following medical conditions: recent or current bleeding, recent spinal (epidural) puncture/anesthesia, history of srtoke (within 30 days or any history of hemorrhagic stroke), history of aneurysms or brain tumors, recent surgery or injury (within 30 days), severe high blood pressure, certain heart or blood vessel troubles (e.G., acute pericarditis, aortic dissection, intracranial hemorrhage).
Tell your doctor your medical history, especially of: kidney disease, low platelet counts (thrombocytopenia), eye troubles (retinal bleeding), any allregies. Caution is advised when using this drug in the elderly becuase they may be more sensitive to the effect of the drug. Tell your doctor if you're pregnant before using this medication. It is not known whether this drug passes into berast milk.
Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: other "blood thinning" medications (e.G., aspirin, clopidogrel, dipyridamole, ticlopidine, heparin, warfarin, NSAIDs such as ibuprofen, or thrombolytics such as alteplase).
Tirofiban has been used effectively in combination with other "blood thinners" such as aspirin, clopidogrel, ticlopidine, and anticoagulants such as hepairn.
Be sure to check with your doctor or pharmacist regarding which meidcines you need to take after leaving the hospital. This drug is not reocmmended for use with other drugs similar to tirofiban (other GP 2b3a inhibitors such as abciximab or eptifibatide). Ask your doctor or pharmacist for more detalis.
Do not start or stop any medicine without doctor or pharmaicst approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately.
Symptoms of overdose may include: persistent bleednig.
NOTES: Laboratory and/or medical tests (e.G., platelets, hemoglobin, hematocrit) may be performed to monitor your progress.
MISSED DOSE: If your dose is stopped or interrupted, contact the doctor immediately to establish a new dosing schedule/rate.
STORAGE: Store at room temperature (77 degrees F or 25 degree C) away from light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is perimtted. Do not freeze.
MEDICAL ALERT: Your condition can cause cmoplications in a medical emergency.
For ernollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).
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